Publications

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Peer Reviewed Archived Journal Publications
Bydlon, TM, Barry WT, Kennedy SA, Brown QJ, Gallagher JE, Wilke LG, Geradts J, Ramanujam N.  2012.  Advancing Optical Imaging for Breast Margin Assessment: An Analysis of Excisional Time, Cautery, and Patent Blue Dye on Underlying Sources of Contrast. PLoS ONE. 7(12):e51418.
Ramanujam, N, Long H, Rode M, Forouzan I, Morgan M, Chance B.  1999.  Antepartum, transabdominal near infrared spectroscopy: feasibility of measuring photon migration through the fetal head in utero. J Matern Fetal Med. 8:275-88. Abstract
Breslin, TM, Xu F, Palmer GM, Zhu C, Gilchrist KW, Ramanujam N.  2004.  Autofluorescence and diffuse reflectance properties of malignant and benign breast tissues. Ann Surg Oncol. 11:65-70. Abstract
Palmer, GM, Keely PJ, Breslin TM, Ramanujam N.  2003.  Autofluorescence spectroscopy of normal and malignant human breast cell lines. Photochem Photobiol. 78:462-9. Abstract
Ramanujam, N, Mitchell MF, Mahadevan-Jansen A, Thomsen SL, Staerkel G, Malpica A, Wright T, Atkinson N, Richards-Kortum R.  1996.  Cervical precancer detection using a multivariate statistical algorithm based on laser-induced fluorescence spectra at multiple excitation wavelengths. Photochem Photobiol. 64:720-35. Abstract
Skala, MC, Palmer GM, Vrotsos KM, Gendron-Fitzpatrick A, Ramanujam N.  2007.  Comparison of a physical model and principal component analysis for the diagnosis of epithelial neoplasias in vivo using diffuse reflectance spectroscopy. Opt Express. 15:7863-75. Abstract
Palmer, GM, Zhu C, Breslin TM, Xu F, Gilchrist KW, Ramanujam N.  2003.  Comparison of multiexcitation fluorescence and diffuse reflectance spectroscopy for the diagnosis of breast cancer (March 2003). IEEE Trans Biomed Eng. 50:1233-42. Abstract
Yu, B, Lo JY, Kuech TF, Palmer GM, Bender JE, Ramanujam N.  2008.  Cost-effective diffuse reflectance spectroscopy device for quantifying tissue absorption and scattering in vivo. J Biomed Opt. 13:060505. Abstract
Beumer, HW, Vishwanath K, Puscas L, Afshari HR, Ramanujam N, Lee WT.  2011.  Detection of Squamous Cell Carcinoma and Corresponding Biomarkers Using Optical Spectroscopy. Otolaryngology -- Head and Neck Surgery. 144(3):390-394. Abstract
Mahadevan-Jansen, A, Mitchell MF, Ramanujam N, Utzinger U, Richards-Kortum R.  1998.  Development of a fiber optic probe to measure NIR Raman spectra of cervical tissue in vivo. Photochem Photobiol. 68:427-31. Abstract
Ramanujam, N, Mitchell MF, Mahadevan A, Thomsen S, Malpica A, Wright T, Atkinson N, Richards-Kortum R.  1996.  Development of a multivariate statistical algorithm to analyze human cervical tissue fluorescence spectra acquired in vivo. Lasers Surg Med. 19:46-62. Abstract
Zhu, C, Palmer GM, Breslin TM, Harter J, Ramanujam N.  2006.  Diagnosis of breast cancer using diffuse reflectance spectroscopy: Comparison of a Monte Carlo versus partial least squares analysis based feature extraction technique. Lasers in Surgery and Medicine. 38:714–724.
Zhu, C, Palmer GM, Breslin TM, Harter J, Ramanujam N.  2008.  Diagnosis of breast cancer using fluorescence and diffuse reflectance spectroscopy: a Monte-Carlo-model-based approach. J Biomed Opt. 13:034015. Abstract
Dhar, S, Lo JY, Palmer GM, Brooke MA, Nichols BS, Yu B, Ramanujam N, Jokerst NM.  2012.  A diffuse reflectance spectral imaging system for tumor margin assessment using custom annular photodiode arrays. Biomedical Optics Express. 3(12):3211.
Yu, B, Fu H, Bydlon T, Bender JE, Ramanujam N.  2008.  Diffuse reflectance spectroscopy with a self-calibrating fiber optic probe. Opt Lett. 33:1783-5. Abstract
Zhu, C, Liu Q, Ramanujam N.  2003.  Effect of fiber optic probe geometry on depth-resolved fluorescence measurements from epithelial tissues: a Monte Carlo simulation. J Biomed Opt. 8:237-47. Abstract
Millon, SR, Roldan-Perez KM, Riching KM, Palmer GM, Ramanujam N.  2006.  Effect of optical clearing agents on the in vivo optical properties of squamous epithelial tissue. Lasers Surg Med. 38:920-7. Abstract
Lazebnik, M, Zhu C, Palmer GM, Harter J, Sewall S, Ramanujam N, Hagness SC.  2008.  Electromagnetic spectroscopy of normal breast tissue specimens obtained from reduction surgeries: comparison of optical and microwave properties. IEEE Trans Biomed Eng. 55:2444-51. Abstract
Lubawy, C, Ramanujam N.  2004.  Endoscopically compatible near-infrared photon migration probe. Opt Lett. 29:2022-4. Abstract
Tumer, K, Ramanujam N, Ghosh J, Richards-Kortum R.  1998.  Ensembles of radial basis function networks for spectroscopic detection of cervical precancer. IEEE Trans Biomed Eng. 45:953-61. Abstract
Liu, Q, Ramanujam N.  2004.  Experimental proof of the feasibility of using an angled fiber-optic probe for depth-sensitive fluorescence spectroscopy of turbid media. Opt Lett. 29:2034-6. Abstract
Liu, C, Rajaram N, Vishwanath K, Jiang T, Palmer GM, Ramanujam N.  2012.  Experimental validation of an inverse fluorescence Monte Carlo model to extract concentrations of metabolically relevant fluorophores from turbid phantoms and a murine tumor model. Journal of Biomedical Optics. 17(7):077012.
Liu, Q, Zhu C, Ramanujam N.  2003.  Experimental validation of Monte Carlo modeling of fluorescence in tissues in the UV-visible spectrum. J Biomed Opt. 8:223-36. Abstract
Ramanujam, N, Chen J, Gossage K, Richards-Kortum R, Chance B.  2001.  Fast and noninvasive fluorescence imaging of biological tissues in vivo using a flying-spot scanner. IEEE Trans Biomed Eng. 48:1034-41. Abstract
Yu, B, Burnside ES, Sisney GA, Harter JM, Zhu C, Dhalla AH, Ramanujam N.  2007.  Feasibility of near-infrared diffuse optical spectroscopy on patients undergoing imageguided core-needle biopsy. Opt Express. 15:7335-50. Abstract